What it takes to forge a successful corporate career is somewhat less opaque than it used to be, but that does not mean that there are not still traps for the unwary. Here, a business insider offers a few tips for avoiding them and moving up to the top of the organization.
More than 20 children needed hospital treatment after Craig Banks and Dominic Evans sold them drugs.
It paves the way for immigration officials to revert to the approach under the Obama administration.
Dementia, the syndrome caused by several brain illnesses affecting memory, motor skills, thinking and behavior, affects 47 million people around the world and is projected to afflict 75 million by 2030, according to the World Health Organization.
It’s a syndrome that’s not only debilitating for the people who live with it but also for their families and caregivers. According to statistics from WHO the economic cost of dementia is roughly $818 billion.
Yet, it’s also one that’s the most poorly understood by researchers. Now, thanks to a $60 million commitment from the US AARP, a London-based fund has closed with $350 million to invest in new medicines to combat dementia and its underlying illnesses.
Initially formed by the UK Department of Health and Social Care and the charity Alzheimer’s Research UK (ARUK) alongside a consortium of pharmaceutical companies, including Biogen, Eli Lilly and Company, GSK, Johnson & Johnson, Otsuka (Astex), Pfizer and Takeda, the Dementia Discovery Fund had initially targeted $200 million to invest in new treatments.
Commitments from other wealthy individuals (like Bill Gates) and interested organizations like (ahem) the NFL Players Association, and UnitedHealth Group helped round out the commitments to get the fund closed at its $350 million hard cap.
Founded in October, 2015 by SV Health Investors, a venture capital and growth equity firm with offices in London and Boston and roughly $2.5 billion under management, the Dementia Discovery Fund has already invested in 16 companies in the U.S. and the U.K. focused on microglial biology and inflammation, mitochondrial dynamics, trafficking and membrane biology and synaptic physiology and functions.
“At the DDF, we are focused on scientific approaches that look beyond the amyloid beta pathway into other areas, such as inflammation, mitochondrial function and the preservation and enhancement of healthy brain cells,” said Kate Bingham, managing partner of SV Health Investors, in a statement. “These areas are highly likely to be important to chronic traumatic encephalopathy or traumatic brain injury, leading to renewed hope for treatment of these terrible disorders.”
For the AARP, the investment in finding cures for dementia is central to the nonprofit’s mission going forward, according to chief executive Jo Ann Jenkins. “Dementia doesn’t just affect those with the disease. It takes a devastating emotional, physical and financial toll on families and caregivers. The projected doubling of the size of the 65+ population over the next generation makes finding new ways to treat dementia, including Alzheimer’s, even more critical,” she said.
The UK system is criticised for being “below average” on preventing deaths from heart attacks, strokes and cancer.
Apple today released the first public beta of iOS 12 for compatible iPhone, iPad, and iPod touch models, enabling users who aren’t signed up for the Apple Developer Program to test the software update ahead of its official release in the fall.
While iOS 12 introduces several new features, it is designed to work on all iPhone, iPad, and iPod touch models that can run iOS 11, and the company says it has focused on bringing performance improvements to both old and new devices.
That said, iOS 12 is pre-release software, so installing the Public Beta on a secondary device is highly recommended. The stability of beta software cannot be guaranteed, as it often contains bugs and issues that have yet to be ironed out, so installing it on your day-to-day device isn’t advised.
Installing the Public Beta shouldn’t take longer than half an hour, but first you should create a backup of your device’s contents and settings. The following step-by-step instructions are given for iPhone, but apply to iPad and iPod touch just the same.
How to Create a Backup of Your Device in iTunes
- Connect your iOS device to a Mac or PC using a Lightning to USB cable.
- Open iTunes.
- Click the device’s icon in the top-left menu.
- Under Backups, click This computer.
- Tick the Encrypt iPhone backup checkbox if you want to back up your login credentials and any Health and HomeKit data.
- Click Back Up Now.
- Click iTunes -> Preferences… in the macOS menu bar.
- Click the Devices tab.
- Right-click (or Ctrl-click) the new backup, and select Archive from the contextual dropdown menu.
How to Enroll in the Apple Beta Software Program
Now that you’ve backed up your device, you’re ready to download the iOS 12 Public Beta. To do so, you must enroll your iPhone, iPad, or iPod touch in the free Apple Beta Software Program.
- Open Safari on your iOS device and navigate to the Apple Beta Software Program.
- Tap the Sign up button, or sign in if you’re already a member.
- Enter your Apple ID credentials and tap the Sign in button.
- Agree to the Apple Beta Software Program terms and conditions if necessary.
- A Guide for Public Betas screen will appear. Select the iOS tab, scroll down to the Get Started section and tap enroll your iOS device.
- On the Enroll Your Devices screen, with the iOS tab selected, scroll down and tap the Download profile button.
- Tap “iPhone” or “iPad” when prompted to choose a device.
- Tap Allow.
- Tap Install and follow the prompts to install the iOS Beta Software Profile.
- Restart your device after installing the profile by tapping the restart popup.
How to Install the iOS 12 Public Beta
Once you’re enrolled in the Apple Beta Software Program, you can install the iOS 12 Public Beta on your iOS device just as you would a regular software update.
- Launch the Settings app on your iPhone, iPad, or iPod touch.
- Tap General.
- Tap Software Update.
- Tap Download and Install.
- Tap Install Now.
If you come across any issues installing the iOS 12 Public Beta, it may help to clear any previous profiles lingering on your device. You can find these in the Settings app under General -> Profile.
Discuss this article in our forums